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Preconception: Naproxen Sodium
Dear Anai,
Hi, I have been trying to conceive for 15 months and this month is looking really good. I have a lot of symptoms. However, I had a horrible migraine a few days ago (CD 19) and I took a naproxin sodium for the pain. I have been informed it is very unsafe. Please provide me with any insight you might have. Does it cause a definite miscarriage? Birth defects? Please advise, I am worried and nervous.
Thank you,
Teresa
Dear Teresa,
As far as we know there is just not enough research done between the use of Naproxen Sodium and it's effects on pregnancy in general. As with anything, special consideration is required - especially when a new life is involved. The first few weeks of life are the most important, so research each prescribed medication and over-the-counter medication. What you do not have in your body naturally, might be harmful when introduced during pregnancy - even when it is considered safe.
Certain things you should know about Naproxen sodium are:
- Consult with your doctor if you are taking Naproxen sodium during and after treatment - it causes anemia.
- It contains high levels of sodium, so people on special diets should not take this medication.
- Naproxen sodium is a blood thinner. Do not take aspirin or eat any foods that will thin your blood such as garlic, raisins, fish.
- This drug may cause vision problems, if you see changes contact your doctor for an eye exam.
- This drug may cause high blood pressure and water retention.
- Total daily dose must not exceed 1,375 milligrams. Make sure your doctor is not over prescribing you.
- Naproxen sodium causes liver and kidney damage when used for an extended period of time.
Other names for Naproxen include:
- Anaprox
- Naprelan
- Naprosyn
- Aleve (sold over-the-counter)
- Naproxen Sod
Pregnancy
Pregnancy Category B: *Reproduction studies have been performed in rats at 20 mg/kg/day (125 mg/m2/day, 0.23 times the human systemic exposure) rabbits at 20 mg/kg/day (220 mg/m2/day, 0.27 times the human systemic exposure) and mice at 170 mg/kg/day (510 mg/m2/day, 0.28 times the human systemic exposure) with no evidence of impaired fertility or harm to the fetus due to the drug. There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, Naprelan should be used during pregnancy only if the potential benefits justify the potential risks to the fetus.
Nursing Mothers
*The Naproxen anion has been found in the milk of lactating women at a concentration of approximately 1% of that found in the plasma. Because of the possible adverse effects of prostaglandin-inhibiting drugs on neonates, use in nursing mothers should be avoided.
*http://www.rxlist.com/cgi/generic/naproxsod_wcp.htm
© Copyright 2004 Anai Rhoads.
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